Prevalência da infecção pelo vírus da hepatite B em um município do interior do estado do Acre, Amazônia Ocidental, Brasil

Rita do Socorro Uchôa da Silva; Isadora Oliveira Morais; Danielly Moreira Gonçalves; Irenilce Souza de Matos; Francileide Ferreira da Rocha; Glivia Maria do Nascimento Torres; Maria Lucimar Almeida da Costa; Sueli Santiago da Silva; Paula Alessandra Martins da Silva; Renata Souza

doi:10.5123/S2176-62232017000300003

Authors

Rita do Socorro Uchôa da Silva Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil. Universidade Federal do Acre, Centro de Ciências da Saúde e Desporto, Rio Branco, Acre, Brasil
Isadora Oliveira Morais Universidade Federal do Acre, Centro de Ciências da Saúde e Desporto, Rio Branco, Acre, Brasil
Danielly Moreira Gonçalves Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil
Irenilce Souza de Matos Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil
Francileide Ferreira da Rocha Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil
Glivia Maria do Nascimento Torres Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil
Maria Lucimar Almeida da Costa Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil
Sueli Santiago da Silva Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil
Paula Alessandra Martins da Silva Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil
Renata Souza Secretaria de Saúde do Estado do Acre, Rio Branco, Acre, Brasil

DOI:

https://doi.org/10.5123/S2176-62232017000300003

Keywords:

Human Viral Hepatitis, Hepatitis B virus, HBsAg, Total Anti-HBc

Abstract

OBJECTIVE:

To estimate the prevalence of hepatitis B virus (HBV) in individuals living in Porto Acre municipality, Acre State, Western Brazilian Amazon.

MATERIALS AND METHODS:

Cross-sectional study carried out with residents of Porto Acre who had attended the basic health units in 2012 were invited to answer a standardized questionnaire and to donate venous blood. As screening, immunochromatographic rapid test (IRT) for hepatitis B (HBsAg) was used, and from whom that was reagent to the IRT, serological tests (HBsAg and total anti-HBc) were performed. The HBeAg, anti-HBe and total anti-HD markers were used exclusively in the samples whose HBsAg remained serologically reagent.

RESULTS:

It was included 646 individuals (4.7% of the population), 57.6% of the female gender. Seventeen individuals (2.6%) were reagent to the IRT for HBsAg and of which in 82.3% (14/17) presented serological confirmation. Total anti-HBc was reactive in 31.9% (206/646) of the subjects, of which 2.2% (14/646) had current HBV and 29.7% (192/646) only evidence of previous infection. Of the 184 (28.5%) children and adolescents included in this study, 9.2% (17/184) had prior contact with HBV. The abusive alcohol intake is correlated to HBsAg and total anti-HBc reactivity, whereas older age, male gender, previous surgeries, and the presence of tattoos were related exclusively to total anti-HBc higher reactivity.

CONCLUSION:

HBsAg seroprevalence was 2.2% and total anti-HBc approximately 32.0%. There was detection of total anti-HBc in 9.2% of the children and adolescents included in the study, evidencing early contact with HBV in this population.