Viral hepatitis: epidemiological, clinical aspects and prevention in municipalities of the Parauapebas Microregion, southeastern Pará State, Brazil

Abstract

INTRODUCTION:

Curionópolis and Canaã dos Carajás are municipalities located at southeast of Pará State, Brazil, with great migration flow due to the influence of mining areas and the implementation of large mining projects, making necessary to know the epidemiological patterns of endemic diseases in that region, such as viral hepatitis.

OBJECTIVES:

To define the incidence of hepatitis A (HAV), B (HBV), C (HCV) and D (HDV) virus infections in serum samples of people from municipalities in Parauapebas Microregion.

MATERIALS AND METHODS:

A quantitative and descriptive study was conducted between August 2012 and September 2014, using data collected randomly from individuals in Canaã dos Carajás and Curionópolis. Blood samples were collected for serological tests of viral hepatitis A, B, C and D by immunoenzymatic technique.

RESULTS:

In Canaã dos Carajás, among the 825 samples, there was a prevalence of 76.4% for anti-HAV; 0.2% were HBsAg+; prevalence of 0.1% anti-HCV was detected; and anti-HD of the HBsAg+ samples was negative. In Curionópolis, among the 376 serum samples, anti-HAV prevalence was 84.8%; 0.5% showed HBsAg+; there was anti-HCV prevalence of 0.5%; and no samples were positive for anti-HD.

CONCLUSION:

It was concluded in laboratory that Curionópolis presented high endemicity for HAV and HBV and low for HCV; Canaã dos Carajás presented high HAV endemicity, HBV intermediate endemicity, and low for HCV. HDV was not found in those populations.