Cytomegalovirus: epidemiology based on seroprevalence data

Abstract

Human cytomegalovirus (HCMV) is one of the main causes of several morbid diseases during pre- and postnatal periods. Seroepidemiologic data indicate that HCMV has a high prevalence worldwide with infection rates varying with social strata and geographic regions. Its high prevalence is mainly associated with socioeconomic factors, poor hygiene, poor sanitary conditions, and cultural standards, especially in developing countries. This article aimed to evaluate factors that contribute to the seroepidemiologic profile of HCMV, as well as investigate its current seroprevalence with respect to geographic location and age.