Aspectos clínicos e epidemiológicos da infecção genital pelo papilomavírus humano em gestantes do município de Imperatriz, estado do Maranhão, Brasil

Graciene Pereira de Sousa; Esther Iris Christina Freifrau von Ledeb; Marizeli Viana de Aragão Araújo; George Alberto da Silva Dias; Elcimara da Paixão Ferreira Chagas; Juarez Antônio Simões Quaresma; Hellen Thaís Fuzii

doi:10.5123/S2176-62232018000300004

Authors

Graciene Pereira de Sousa Universidade Federal do Pará, Núcleo de Medicina Tropical, Laboratório de Imunopatologia, Belém, Pará, Brasil
Esther Iris Christina Freifrau von Ledeb Universidade Federal do Pará, Instituto de Ciências Biológicas, Belém, Pará, Brasil
Marizeli Viana de Aragão Araújo Universidade Federal do Pará, Instituto de Ciências da Saúde, Belém, Pará, Brasil
George Alberto da Silva Dias Universidade do Estado do Pará, Centro de Ciências Biológicas e da Saúde, Belém, Pará, Brasil
Elcimara da Paixão Ferreira Chagas Universidade Federal do Pará, Núcleo de Medicina Tropical, Laboratório de Imunopatologia, Belém, Pará, Brasil
Juarez Antônio Simões Quaresma Universidade do Estado do Pará, Centro de Ciências Biológicas e da Saúde, Belém, Pará, Brasil
Hellen Thaís Fuzii Universidade Federal do Pará, Núcleo de Medicina Tropical, Laboratório de Imunopatologia, Belém, Pará, Brasil

DOI:

https://doi.org/10.5123/S2176-62232018000300004

Keywords:

Human Papillomavirus, Pregnancy, Risk Factors

Abstract

OBJECTIVE:

To determine the prevalence of cervical human papillomavirus (HPV) infection in pregnant women from the Municipality of Imperatriz, Maranhão State, Brazil. Materials and Methods: HPV-DNA was detected by polymerase chain reaction from cervicovaginal material collected with cervical brush from 167 pregnant women who answered a questionnaire with sociodemographic, behavioral and reproductive data. Results: HPV genital infection prevalence was 17.36%. Single pregnant women had four times higher chances of HPV infection than married pregnant women (OR = 4.03; p = 0.0046). Primigravidas had higher infection prevalence (29.03%), statistically significant (OR = 3.42; p = 0.001). Conclusion: With these results it is possible to conclude that pregnant women who are more susceptible to HPV infection are young women, pregnant for the first time, and in unstable marital relationships, which shows the need to combat HPV infection by implanting or expanding sexual education and family planning programs focused on young people, in addition to expanding the continued anti-HPV vaccination programs.