Micose fungoide hipocromiante em grávida

Carla Andréa Avelar Pires; Ana Thaís Machado Moutinho; Maria Amélia Lopes do Santos; Leonidas Braga Dias Junior; Alena Margareth Darwich Mendes; Francisca Regina Oliveira Carneiro

doi:10.5123/S2176-62232015000200009

Authors

Carla Andréa Avelar Pires Universidade Federal do Pará, Belém, Pará, Brasil. Universidade do Estado do Pará, Belém, Pará, Brasil
Ana Thaís Machado Moutinho Serviço de Dermatologia, Universidade do Estado do Pará, Belém, Pará, Brasil
Maria Amélia Lopes do Santos Universidade do Estado do Pará, Belém, Pará, Brasil
Leonidas Braga Dias Junior Universidade do Estado do Pará, Belém, Pará, Brasil
Alena Margareth Darwich Mendes Universidade do Estado do Pará, Belém, Pará, Brasil. Centro Universitário do Estado do Pará, Belém, Pará, Brasil
Francisca Regina Oliveira Carneiro Universidade do Estado do Pará, Belém, Pará, Brasil

DOI:

https://doi.org/10.5123/S2176-62232015000200009

Keywords:

Pregnant Women, Lymphoma, T-Cell, Cutaneous, CD4-Positive T-Lymphocytes

Abstract

Mycosis fungoides (MF) is the most common primary cutaneous lymphoma, characterized by epidermotropism of monoclonal T-cell lymphoma. It was presented a case of a patient, 39 years old, 22 weeks pregnant, with small white spots in the gluteal region since three years ago which increased in the first two months of pregnancy. The exam showed hypochromic stains of varying sizes in the gluteal region and legs and also erythematous plaque infiltrated on the left buttock. Two biopsies were performed; both showed epidermis with lymphocytes in Pautrier's microabscesses. In the upper dermis was observed fibroplasia. Immunohistochemistry revealed a CD4-positive T lymphocytes. The patient had no palpable lymph nodes and no change in the hematology test and after performed the diagnosis of MF, she was referred to a reference hospital.