Perfil dos exames citológicos do colo do útero realizados no Laboratório Central do Estado do Pará, Brasil

Maísa Silva de Sousa; Aline Silva de Sousa Canto; Mihoko Yamamoto Tsutsumi; Marinalva Cardoso Maciel; Luiz Carlos Zeferino

doi:10.5123/S2176-62232011000200004

Authors

Maísa Silva de Sousa Curso de Pós-graduação em Bioestatística, Instituto de Ciências Exatas e Naturais, Núcleo de Medicina Tropical, Universidade Federal do Pará, Belém, Pará, Brasil
Aline Silva de Sousa Canto Curso de Especialização em Análises Clínicas, Faculdade de Farmácia, Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, Pará, Brasil
Mihoko Yamamoto Tsutsumi Laboratório de Citopatologia, Faculdade de Biomedicina, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brasil
Marinalva Cardoso Maciel Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará, Belém, Pará, Brasil
Luiz Carlos Zeferino Departamento de Tocoginecologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brasil

DOI:

https://doi.org/10.5123/S2176-62232011000200004

Keywords:

Public Health, Unified Health System, Primary Health Care, Women's Health Services, Uterine Cervical Neoplasms

Abstract

ABSTRACT

This study aimed to identify the profile of cervical cytological exams by analyzing all slides collected in 16 cities in Pará State and sent to the Pará State Central Laboratory (Lacen-PA) during 2008. Data were analyzed using the binomial and Fisher's exact tests to identify the statistical significance of the proportional differences based on a 95% confidence level. Of the 26,203 exams, approximately 3.7% (n = 970) were considered unsatisfactory, and 4.05% (n = 1060) showed some type of cytological change. The incidence of atypical cells suggestive of potentially malignant lesions (high-grade and microinvasive intraepithelial lesions) and of invasive cancer were 0.9% (n = 236) and 0.1% (n = 25), respectively. Exam results suggestive of invasive cancer were found in 0.17% (10/5,995) of women who had never had cervical cancer preventive examinations (Pap smears) and in 0.08% (14/17,932) of women who had already undergone the exam (p = 0.0301). In the Brazilian literature, the incidence of cytological changes suggestive of invasive cancer was highest among women diagnosed via primary care services. That incidence was higher for women who had never had the exam. This finding may indicate a gap in cervical cancer prevention coverage in Pará State.